Co-administration of temozolomide (TMZ) and the experimental therapeutic targeting miR-10b, profoundly affects the tumorigenic phenotype of human glioblastoma cells

Introduction: Recent studies have shown that miRNA-10b is highly expressed in high-grade glioblastoma multiforme (GBM), and its inhibition leads to deregulation of multiple pathways in tumorigenesis, resulting in repression of tumor growth and increased apoptosis. Thus, we hypothesized that suppress...

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Detalles Bibliográficos
Autores principales: Chen, Ming, Kim, Bryan, Robertson, Neil, Mondal, Sujan Kumar, Medarova, Zdravka, Moore, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10311069/
https://www.ncbi.nlm.nih.gov/pubmed/37398551
http://dx.doi.org/10.3389/fmolb.2023.1179343

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10311069/
https://www.ncbi.nlm.nih.gov/pubmed/37398551
http://dx.doi.org/10.3389/fmolb.2023.1179343

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