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Co-administration of temozolomide (TMZ) and the experimental therapeutic targeting miR-10b, profoundly affects the tumorigenic phenotype of human glioblastoma cells
Introduction: Recent studies have shown that miRNA-10b is highly expressed in high-grade glioblastoma multiforme (GBM), and its inhibition leads to deregulation of multiple pathways in tumorigenesis, resulting in repression of tumor growth and increased apoptosis. Thus, we hypothesized that suppress...
Autores principales: | Chen, Ming, Kim, Bryan, Robertson, Neil, Mondal, Sujan Kumar, Medarova, Zdravka, Moore, Anna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10311069/ https://www.ncbi.nlm.nih.gov/pubmed/37398551 http://dx.doi.org/10.3389/fmolb.2023.1179343 |
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