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Polymer-mediated and ultrasound-assisted crystallization of ropivacaine: Crystal growth and morphology modulation
The objective of this research was to modify the crystal shape and size of poorly water-soluble drug ropivacaine, and to reveal the effects of polymeric additive and ultrasound on crystal nucleation and growth. Ropivacaine often grow as needle-like crystals extended along the a-axis and the shape wa...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10311179/ https://www.ncbi.nlm.nih.gov/pubmed/37321071 http://dx.doi.org/10.1016/j.ultsonch.2023.106475 |