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Clinical associations and characteristics of the polyspecific intrathecal immune response in elderly patients with non-multiple sclerosis chronic autoimmune-inflammatory neurological diseases – a retrospective cross-sectional study

INTRODUCTION: The polyspecific intrathecal immune response (PSIIR), aka MRZ reaction (M = measles, R = rubella, Z = zoster, optionally Herpes simplex virus, HSV) is defined as intrathecal immunoglobulin synthesis (IIS) for two or more unrelated viruses. Although an established cerebrospinal fluid (C...

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Detalles Bibliográficos
Autores principales: Brauchle, Felix, Rapp, Daniel, Senel, Makbule, Huss, André, Dreyhaupt, Jens, Klose, Veronika, Süße, Marie, Stürner, Klarissa Hanja, Leypoldt, Frank, Tumani, Hayrettin, Lewerenz, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10311206/
https://www.ncbi.nlm.nih.gov/pubmed/37396770
http://dx.doi.org/10.3389/fneur.2023.1193015