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Cell type matching across species using protein embeddings and transfer learning

MOTIVATION: Knowing the relation between cell types is crucial for translating experimental results from mice to humans. Establishing cell type matches, however, is hindered by the biological differences between the species. A substantial amount of evolutionary information between genes that could b...

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Detalles Bibliográficos
Autores principales: Biharie, Kirti, Michielsen, Lieke, Reinders, Marcel J T, Mahfouz, Ahmed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10311290/
https://www.ncbi.nlm.nih.gov/pubmed/37387141
http://dx.doi.org/10.1093/bioinformatics/btad248