RNA design via structure-aware multifrontier ensemble optimization

MOTIVATION: RNA design is the search for a sequence or set of sequences that will fold to desired structure, also known as the inverse problem of RNA folding. However, the sequences designed by existing algorithms often suffer from low ensemble stability, which worsens for long sequence design. Addi...

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Detalles Bibliográficos
Autores principales: Zhou, Tianshuo, Dai, Ning, Li, Sizhen, Ward, Max, Mathews, David H, Huang, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
General Computational Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10311297/
https://www.ncbi.nlm.nih.gov/pubmed/37387188
http://dx.doi.org/10.1093/bioinformatics/btad252

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10311297/
https://www.ncbi.nlm.nih.gov/pubmed/37387188
http://dx.doi.org/10.1093/bioinformatics/btad252

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