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RNA design via structure-aware multifrontier ensemble optimization
MOTIVATION: RNA design is the search for a sequence or set of sequences that will fold to desired structure, also known as the inverse problem of RNA folding. However, the sequences designed by existing algorithms often suffer from low ensemble stability, which worsens for long sequence design. Addi...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10311297/ https://www.ncbi.nlm.nih.gov/pubmed/37387188 http://dx.doi.org/10.1093/bioinformatics/btad252 |