SynBa: improved estimation of drug combination synergies with uncertainty quantification

MOTIVATION: There exists a range of different quantification frameworks to estimate the synergistic effect of drug combinations. The diversity and disagreement in estimates make it challenging to determine which combinations from a large drug screening should be proceeded with. Furthermore, the lack...

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Detalles Bibliográficos
Autores principales: Zhang, Haoting, Ek, Carl Henrik, Rattray, Magnus, Milo, Marta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Biomedical Informatics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10311304/
https://www.ncbi.nlm.nih.gov/pubmed/37387161
http://dx.doi.org/10.1093/bioinformatics/btad240

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10311304/
https://www.ncbi.nlm.nih.gov/pubmed/37387161
http://dx.doi.org/10.1093/bioinformatics/btad240

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