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SynBa: improved estimation of drug combination synergies with uncertainty quantification
MOTIVATION: There exists a range of different quantification frameworks to estimate the synergistic effect of drug combinations. The diversity and disagreement in estimates make it challenging to determine which combinations from a large drug screening should be proceeded with. Furthermore, the lack...
Autores principales: | Zhang, Haoting, Ek, Carl Henrik, Rattray, Magnus, Milo, Marta |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10311304/ https://www.ncbi.nlm.nih.gov/pubmed/37387161 http://dx.doi.org/10.1093/bioinformatics/btad240 |
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