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Higher-order genetic interaction discovery with network-based biological priors

MOTIVATION: Complex phenotypes, such as many common diseases and morphological traits, are controlled by multiple genetic factors, namely genetic mutations and genes, and are influenced by environmental conditions. Deciphering the genetics underlying such traits requires a systemic approach, where m...

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Detalles Bibliográficos
Autores principales: Pellizzoni, Paolo, Muzio, Giulia, Borgwardt, Karsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10311320/
https://www.ncbi.nlm.nih.gov/pubmed/37387173
http://dx.doi.org/10.1093/bioinformatics/btad273