scKINETICS: inference of regulatory velocity with single-cell transcriptomics data

MOTIVATION: Transcriptional dynamics are governed by the action of regulatory proteins and are fundamental to systems ranging from normal development to disease. RNA velocity methods for tracking phenotypic dynamics ignore information on the regulatory drivers of gene expression variability through...

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Detalles Bibliográficos
Autores principales: Burdziak, Cassandra, Zhao, Chujun Julia, Haviv, Doron, Alonso-Curbelo, Direna, Lowe, Scott W, Pe’er, Dana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Regulatory and Functional Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10311321/
https://www.ncbi.nlm.nih.gov/pubmed/37387147
http://dx.doi.org/10.1093/bioinformatics/btad267

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10311321/
https://www.ncbi.nlm.nih.gov/pubmed/37387147
http://dx.doi.org/10.1093/bioinformatics/btad267

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