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scKINETICS: inference of regulatory velocity with single-cell transcriptomics data
MOTIVATION: Transcriptional dynamics are governed by the action of regulatory proteins and are fundamental to systems ranging from normal development to disease. RNA velocity methods for tracking phenotypic dynamics ignore information on the regulatory drivers of gene expression variability through...
Autores principales: | Burdziak, Cassandra, Zhao, Chujun Julia, Haviv, Doron, Alonso-Curbelo, Direna, Lowe, Scott W, Pe’er, Dana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10311321/ https://www.ncbi.nlm.nih.gov/pubmed/37387147 http://dx.doi.org/10.1093/bioinformatics/btad267 |
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