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Characterizing alternative splicing effects on protein interaction networks with LINDA

MOTIVATION: Alternative RNA splicing plays a crucial role in defining protein function. However, despite its relevance, there is a lack of tools that characterize effects of splicing on protein interaction networks in a mechanistic manner (i.e. presence or absence of protein–protein interactions due...

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Detalles Bibliográficos
Autores principales: Gjerga, Enio, Naarmann-de Vries, Isabel S, Dieterich, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10311343/
https://www.ncbi.nlm.nih.gov/pubmed/37387163
http://dx.doi.org/10.1093/bioinformatics/btad224