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Reference panel-guided super-resolution inference of Hi-C data

MOTIVATION: Accurately assessing contacts between DNA fragments inside the nucleus with Hi-C experiment is crucial for understanding the role of 3D genome organization in gene regulation. This challenging task is due in part to the high sequencing depth of Hi-C libraries required to support high-res...

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Detalles Bibliográficos
Autores principales: Zhang, Yanlin, Blanchette, Mathieu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10311349/
https://www.ncbi.nlm.nih.gov/pubmed/37387127
http://dx.doi.org/10.1093/bioinformatics/btad266