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RYR2-ryanodinopathies: from calcium overload to calcium deficiency

The sarcoplasmatic reticulum (SR) cardiac ryanodine receptor/calcium release channel RyR2 is an essential regulator of cardiac excitation–contraction coupling and intracellular calcium homeostasis. Mutations of the RYR2 are the cause of rare, potentially lethal inherited arrhythmia disorders. Catech...

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Detalles Bibliográficos
Autores principales: Steinberg, Christian, Roston, Thomas M, van der Werf, Christian, Sanatani, Shubhayan, Chen, S R Wayne, Wilde, Arthur A M, Krahn, Andrew D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10311407/
https://www.ncbi.nlm.nih.gov/pubmed/37387319
http://dx.doi.org/10.1093/europace/euad156