Elevated serum polyclonal immunoglobulin free light chains in patients with severe asthma

Background: Inflammation plays a pivotal role in the pathophysiology of asthma. Free light chains (FLC) can cause inflammation by mast cell antigen-activation. Serum immunoglobulin (Ig) FLC κ, but not λ, were shown elevated in adult males with asthma. We sought to investigate if serum Ig FLC concent...

Descripción completa

Detalles Bibliográficos
Autores principales: Basile, Umberto, Santini, Giuseppe, Napodano, Cecilia, Macis, Giuseppe, Pocino, Krizia, Gulli, Francesca, Malerba, Mario, Bush, Andrew, Adcock, Ian M., Montuschi, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10311563/
https://www.ncbi.nlm.nih.gov/pubmed/37397489
http://dx.doi.org/10.3389/fphar.2023.1126535

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10311563/
https://www.ncbi.nlm.nih.gov/pubmed/37397489
http://dx.doi.org/10.3389/fphar.2023.1126535

Ejemplares similares