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Elevated serum polyclonal immunoglobulin free light chains in patients with severe asthma

Background: Inflammation plays a pivotal role in the pathophysiology of asthma. Free light chains (FLC) can cause inflammation by mast cell antigen-activation. Serum immunoglobulin (Ig) FLC κ, but not λ, were shown elevated in adult males with asthma. We sought to investigate if serum Ig FLC concent...

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Detalles Bibliográficos
Autores principales:	Basile, Umberto, Santini, Giuseppe, Napodano, Cecilia, Macis, Giuseppe, Pocino, Krizia, Gulli, Francesca, Malerba, Mario, Bush, Andrew, Adcock, Ian M., Montuschi, Paolo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10311563/ https://www.ncbi.nlm.nih.gov/pubmed/37397489 http://dx.doi.org/10.3389/fphar.2023.1126535

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