Liquid–Liquid Phase Separation Primes Spider Silk Proteins for Fiber Formation via a Conditional Sticker Domain

[Image: see text] Many protein condensates can convert to fibrillar aggregates, but the underlying mechanisms are unclear. Liquid–liquid phase separation (LLPS) of spider silk proteins, spidroins, suggests a regulatory switch between both states. Here, we combine microscopy and native mass spectrome...

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Detalles Bibliográficos
Autores principales: Leppert, Axel, Chen, Gefei, Lama, Dilraj, Sahin, Cagla, Railaite, Vaida, Shilkova, Olga, Arndt, Tina, Marklund, Erik G., Lane, David P., Rising, Anna, Landreh, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10311596/
https://www.ncbi.nlm.nih.gov/pubmed/37084706
http://dx.doi.org/10.1021/acs.nanolett.3c00773

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10311596/
https://www.ncbi.nlm.nih.gov/pubmed/37084706
http://dx.doi.org/10.1021/acs.nanolett.3c00773

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