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BMI-1 activates hepatic stellate cells to promote the epithelial-mesenchymal transition of colorectal cancer cells

BACKGROUND: Activated hepatic stellate cells (aHSCs) are the major source of cancer-associated fibroblasts in the liver. Although the crosstalk between aHSCs and colorectal cancer (CRC) cells supports liver metastasis (LM), the mechanisms are largely unknown. AIM: To explore the role of BMI-1, a pol...

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Detalles Bibliográficos
Autores principales: Jiang, Zhong-Yang, Ma, Xi-Mei, Luan, Xiao-Hui, Liuyang, Zhen-Yu, Hong, Yi-Yang, Dai, Yuan, Dong, Qing-Hua, Wang, Guan-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10311613/
https://www.ncbi.nlm.nih.gov/pubmed/37398890
http://dx.doi.org/10.3748/wjg.v29.i23.3606