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The volatile anesthetic isoflurane differentially inhibits voltage-gated sodium channel currents between pyramidal and parvalbumin neurons in the prefrontal cortex

BACKGROUND: How volatile anesthetics work remains poorly understood. Modulations of synaptic neurotransmission are the direct cellular mechanisms of volatile anesthetics in the central nervous system. Volatile anesthetics such as isoflurane may reduce neuronal interaction by differentially inhibitin...

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Detalles Bibliográficos
Autores principales: Qiu, Jingxuan, Yang, Yaoxin, Liu, Jin, Zhao, Wenling, Li, Qian, Zhu, Tao, Liang, Peng, Zhou, Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10311640/
https://www.ncbi.nlm.nih.gov/pubmed/37396397
http://dx.doi.org/10.3389/fncir.2023.1185095