Genetically programmed retinoic acid deficiency during gastrulation phenocopies most known developmental defects due to acute prenatal alcohol exposure in FASD

Fetal Alcohol Spectrum Disorder (FASD) arises from maternal consumption of alcohol during pregnancy affecting 2%–5% of the Western population. In Xenopus laevis studies, we showed that alcohol exposure during early gastrulation reduces retinoic acid (RA) levels at this critical embryonic stage induc...

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Detalles Bibliográficos
Autores principales: Petrelli, B., Oztürk, A., Pind, M., Ayele, H., Fainsod, A., Hicks, G. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10311642/
https://www.ncbi.nlm.nih.gov/pubmed/37397253
http://dx.doi.org/10.3389/fcell.2023.1208279

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10311642/
https://www.ncbi.nlm.nih.gov/pubmed/37397253
http://dx.doi.org/10.3389/fcell.2023.1208279

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