Covalent Proteins as Targeted Radionuclide Therapies Enhance Antitumor Effects

[Image: see text] Molecularly targeted radionuclide therapies (TRTs) struggle with balancing efficacy and safety, as current strategies to increase tumor absorption often alter drug pharmacokinetics to prolong circulation and normal tissue irradiation. Here we report the first covalent protein TRT,...

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Detalles Bibliográficos
Autores principales: Klauser, Paul C., Chopra, Shalini, Cao, Li, Bobba, Kondapa Naidu, Yu, Bingchen, Seo, Youngho, Chan, Emily, Flavell, Robert R., Evans, Michael J., Wang, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10311652/
https://www.ncbi.nlm.nih.gov/pubmed/37396859
http://dx.doi.org/10.1021/acscentsci.3c00288

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10311652/
https://www.ncbi.nlm.nih.gov/pubmed/37396859
http://dx.doi.org/10.1021/acscentsci.3c00288

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