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Covalent Proteins as Targeted Radionuclide Therapies Enhance Antitumor Effects
[Image: see text] Molecularly targeted radionuclide therapies (TRTs) struggle with balancing efficacy and safety, as current strategies to increase tumor absorption often alter drug pharmacokinetics to prolong circulation and normal tissue irradiation. Here we report the first covalent protein TRT,...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10311652/ https://www.ncbi.nlm.nih.gov/pubmed/37396859 http://dx.doi.org/10.1021/acscentsci.3c00288 |