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Aminobenzoic Acid Derivatives Obstruct Induced Fit in the Catalytic Center of the Ribosome

[Image: see text] The Escherichia coli (E. coli) ribosome can incorporate a variety of non-l-α-amino acid monomers into polypeptide chains in vitro but with poor efficiency. Although these monomers span a diverse set of compounds, there exists no high-resolution structural information regarding thei...

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Detalles Bibliográficos
Autores principales: Majumdar, Chandrima, Walker, Joshua A., Francis, Matthew B., Schepartz, Alanna, Cate, Jamie H. D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10311655/
https://www.ncbi.nlm.nih.gov/pubmed/37396857
http://dx.doi.org/10.1021/acscentsci.3c00153