Mechanochemical Oxidative Degradation of Thienopyridine Containing Drugs: Toward a Simple Tool for the Prediction of Drug Stability

[Image: see text] The long-term stability of an active-pharmaceutical ingredient and its drug products plays an important role in the licensing process of new pharmaceuticals and for the application of the drug at the patient. It is, however, difficult to predict degradation profiles at early stages...

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Detalles Bibliográficos
Autores principales: Krake, Everaldo F., Backer, Laura, Andres, Benjamin, Baumann, Wolfgang, Handler, Norbert, Buschmann, Helmut, Holzgrabe, Ulrike, Bolm, Carsten, Beweries, Torsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10311657/
https://www.ncbi.nlm.nih.gov/pubmed/37396854
http://dx.doi.org/10.1021/acscentsci.3c00167

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10311657/
https://www.ncbi.nlm.nih.gov/pubmed/37396854
http://dx.doi.org/10.1021/acscentsci.3c00167

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