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Thiol-Mediated Uptake of a Cysteine-Containing Nanobody for Anticancer Drug Delivery

[Image: see text] The identification of tumor-specific biomarkers is one of the bottlenecks in the development of cancer therapies. Previous work revealed altered surface levels of reduced/oxidized cysteines in many cancers due to overexpression of redox-controlling proteins such as protein disulfid...

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Detalles Bibliográficos
Autores principales: Goerdeler, Felix, Reuber, Emelie E., Lühle, Jost, Leichnitz, Sabrina, Freitag, Anika, Nedielkov, Ruslan, Groza, Raluca, Ewers, Helge, Möller, Heiko M., Seeberger, Peter H., Moscovitz, Oren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10311659/
https://www.ncbi.nlm.nih.gov/pubmed/37396861
http://dx.doi.org/10.1021/acscentsci.3c00177