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C–H Glycosylation of Native Carboxylic Acids: Discovery of Antidiabetic SGLT-2 Inhibitors

[Image: see text] C-Glycosides are critical motifs embedded in many bioactive natural products. The inert C-glycosides are privileged structures for developing therapeutic agents owing to their high chemical and metabolic stability. Despite the comprehensive strategies and tactics established in the...

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Detalles Bibliográficos
Autores principales: Wang, Sanshan, Chen, Kaiqi, Guo, Fusheng, Zhu, Wenneng, Liu, Chendi, Dong, Haoran, Yu, Jin-Quan, Lei, Xiaoguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10311666/
https://www.ncbi.nlm.nih.gov/pubmed/37396867
http://dx.doi.org/10.1021/acscentsci.3c00201