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Collagen turnover is associated with cardiovascular autonomic and peripheral neuropathy in type 1 diabetes: novel pathophysiological mechanism?

BACKGROUND: Diabetic cardiovascular autonomic neuropathy (CAN) and distal symmetrical polyneuropathy (DSPN) are severe diabetic complications. Collagen type VI (COL6) and III (COL3) have been associated with nerve function. We investigated if markers of COL6 formation (PRO-C6) and COL3 degradation (...

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Detalles Bibliográficos
Autores principales: Hansen, Christian S., Rasmussen, Daniel G. K., Hansen, Tine W., Nielsen, Signe Holm, Theilade, Simone, Karsdal, Morten A., Genovese, Federica, Rossing, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10311721/
https://www.ncbi.nlm.nih.gov/pubmed/37386485
http://dx.doi.org/10.1186/s12933-023-01891-8