Inhibition of DRP1-dependent mitochondrial fission by Mdivi-1 alleviates atherosclerosis through the modulation of M1 polarization

BACKGROUND: Inflammation and immune dysfunction with classically activated macrophages(M1) infiltration are important mechanisms in the progression of atherosclerosis (AS). Dynamin-related protein 1 (DRP1)-dependent mitochondrial fission is a novel target for alleviating inflammatory diseases. This...

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Detalles Bibliográficos
Autores principales: Su, Ze-da-zhong, Li, Chun-qiu, Wang, Hua-wei, Zheng, Min-ming, Chen, Qing-wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10311781/
https://www.ncbi.nlm.nih.gov/pubmed/37386574
http://dx.doi.org/10.1186/s12967-023-04270-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10311781/
https://www.ncbi.nlm.nih.gov/pubmed/37386574
http://dx.doi.org/10.1186/s12967-023-04270-9

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