Deconvolution of whole blood transcriptomics identifies changes in immune cell composition in patients with systemic lupus erythematosus (SLE) treated with mycophenolate mofetil

BACKGROUND: Systemic lupus erythematosus (SLE) is a clinically and biologically heterogeneous autoimmune disease. We explored whether the deconvolution of whole blood transcriptomic data could identify differences in predicted immune cell frequency between active SLE patients, and whether these diff...

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Detalles Bibliográficos
Autores principales: Akthar, Mumina, Nair, Nisha, Carter, Lucy M., Vital, Edward M., Sutton, Emily, McHugh, Neil, Bruce, Ian N., Reynolds, John A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10311871/
https://www.ncbi.nlm.nih.gov/pubmed/37391799
http://dx.doi.org/10.1186/s13075-023-03089-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10311871/
https://www.ncbi.nlm.nih.gov/pubmed/37391799
http://dx.doi.org/10.1186/s13075-023-03089-5

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