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Associations between polygenic risk score and covid-19 susceptibility and severity across ethnic groups: UK Biobank analysis

BACKGROUND: COVID-19 manifests with huge heterogeneity in susceptibility and severity outcomes. UK Black Asian and Minority Ethnic (BAME) groups have demonstrated disproportionate burdens. Some variability remains unexplained, suggesting potential genetic contribution. Polygenic Risk Scores (PRS) ca...

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Detalles Bibliográficos
Autores principales: Farooqi, Raabia, Kooner, Jaspal S., Zhang, Weihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10311902/
https://www.ncbi.nlm.nih.gov/pubmed/37386504
http://dx.doi.org/10.1186/s12920-023-01584-x