Modifying antibody-FcRn interactions to increase the transport of antibodies through the blood-brain barrier

The blood-brain barrier (BBB) largely excludes antibodies from entering the central nervous system, thus limiting the potential of therapeutic antibodies to treat conditions such as neurodegenerative diseases and neuro-psychiatric disorders. Here, we demonstrate that the transport of human antibodie...

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Detalles Bibliográficos
Autores principales: Tien, Jason, Leonoudakis, Dmitri, Petrova, Ralitsa, Trinh, Vivian, Taura, Tetsuya, Sengupta, Debapriya, Jo, Lisa, Sho, Angela, Yun, Yong, Doan, Eric, Jamin, Anita, Hallak, Hussein, Wilson, David S., Stratton, Jennifer R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312019/
https://www.ncbi.nlm.nih.gov/pubmed/37381177
http://dx.doi.org/10.1080/19420862.2023.2229098

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312019/
https://www.ncbi.nlm.nih.gov/pubmed/37381177
http://dx.doi.org/10.1080/19420862.2023.2229098

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