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Short-term immune-checkpoint inhibition partially rescues perturbed bone marrow hematopoiesis in mismatch-repair deficient tumors

Wide-spread cancer-related immunosuppression often curtails immune-mediated antitumoral responses. Immune-checkpoint inhibitors (ICIs) have become a state-of-the-art treatment modality for mismatch repair-deficient (dMMR) tumors. Still, the impact of ICI-treatment on bone marrow perturbations is lar...

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Detalles Bibliográficos
Autores principales: Krone, Paula, Wolff, Annabell, Teichmann, Julia, Maennicke, Johanna, Henne, Julia, Engster, Leonie, Salewski, Inken, Bergmann, Wendy, Junghanss, Christian, Maletzki, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312035/
https://www.ncbi.nlm.nih.gov/pubmed/37396958
http://dx.doi.org/10.1080/2162402X.2023.2230669