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A combinatorial approach to uncover an additional Integrator subunit

RNA polymerase II (RNAPII) controls expression of all protein-coding genes and most noncoding loci in higher eukaryotes. Calibrating RNAPII activity requires an assortment of polymerase-associated factors that are recruited at sites of active transcription. The Integrator complex is one of the most...

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Detalles Bibliográficos
Autores principales: Offley, Sarah R., Pfleiderer, Moritz M., Zucco, Avery, Fraudeau, Angelique, Welsh, Sarah A., Razew, Michal, Galej, Wojciech P., Gardini, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312363/
https://www.ncbi.nlm.nih.gov/pubmed/36920904
http://dx.doi.org/10.1016/j.celrep.2023.112244