A conserved epitope in VAR2CSA is targeted by a cross-reactive antibody originating from Plasmodium vivax Duffy binding protein

During Plasmodium falciparum infection in pregnancy, VAR2CSA is expressed on the surface of infected erythrocytes (IEs) and mediates their sequestration in the placenta. As a result, antibodies to VAR2CSA are largely restricted to women who were infected during pregnancy. However, we discovered that...

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Detalles Bibliográficos
Autores principales: Iyamu, Uwa, Vinals, Daniel Ferrer, Tornyigah, Bernard, Arango, Eliana, Bhat, Rakesh, Adra, Trixie Rae, Grewal, Simranjit, Martin, Kimberly, Maestre, Amanda, Overduin, Michael, Hazes, Bart, Yanow, Stephanie K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Cellular and Infection Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312377/
https://www.ncbi.nlm.nih.gov/pubmed/37396303
http://dx.doi.org/10.3389/fcimb.2023.1202276

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312377/
https://www.ncbi.nlm.nih.gov/pubmed/37396303
http://dx.doi.org/10.3389/fcimb.2023.1202276

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