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A conserved epitope in VAR2CSA is targeted by a cross-reactive antibody originating from Plasmodium vivax Duffy binding protein
During Plasmodium falciparum infection in pregnancy, VAR2CSA is expressed on the surface of infected erythrocytes (IEs) and mediates their sequestration in the placenta. As a result, antibodies to VAR2CSA are largely restricted to women who were infected during pregnancy. However, we discovered that...
Autores principales: | Iyamu, Uwa, Vinals, Daniel Ferrer, Tornyigah, Bernard, Arango, Eliana, Bhat, Rakesh, Adra, Trixie Rae, Grewal, Simranjit, Martin, Kimberly, Maestre, Amanda, Overduin, Michael, Hazes, Bart, Yanow, Stephanie K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312377/ https://www.ncbi.nlm.nih.gov/pubmed/37396303 http://dx.doi.org/10.3389/fcimb.2023.1202276 |
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