Metformin is associated with improved clinical outcomes in patients with melanoma: a retrospective, multi-institutional study

BACKGROUND: Pre-clinical studies have shown that metformin reduces intratumoral hypoxia, improves T-cell function, and increases sensitivity to PD-1 blockade, and metformin exposure has been associated with improved clinical outcomes in various types of cancer. However, the impact of this drug in di...

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Detalles Bibliográficos
Autores principales: Augustin, Ryan C., Huang, Ziyu, Ding, Fei, Zhai, Shuyan, McArdle, Jennifer, Santisi, Anthony, Davis, Michael, Sander, Cindy, Davar, Diwakar, Kirkwood, John M., Delgoffe, Greg M., Warner, Allison Betof, Najjar, Yana G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312386/
https://www.ncbi.nlm.nih.gov/pubmed/37397389
http://dx.doi.org/10.3389/fonc.2023.1075823

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312386/
https://www.ncbi.nlm.nih.gov/pubmed/37397389
http://dx.doi.org/10.3389/fonc.2023.1075823

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