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Evaluation of efficacy and safety of clobazam as an add-on drug in the treatment of generalized tonic-clonic seizure not controlled with valproic acid monotherapy

BACKGROUND: Epilepsy is one of the major neuron-damaging neurological disorders. Generalized tonic-clonic seizure (GTCS) is the commonest one. Refractory patterns cannot be controlled by simple monotherapy with antiepileptic drugs (AEDs). Valproic acid (VPA) is one of the widely prescribed AEDs but...

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Detalles Bibliográficos
Autores principales: Das, Somenath, Mandal, Sonai, Maiti, Tamoghna, Mukhopadhyay, Olivia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312407/
https://www.ncbi.nlm.nih.gov/pubmed/37397124
http://dx.doi.org/10.4103/jehp.jehp_1347_22