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Chikungunya virus glycoproteins transform macrophages into productive viral dissemination vessels

Despite their role as innate sentinels, macrophages are cellular reservoirs for chikungunya virus (CHIKV), a highly pathogenic arthropod-borne alphavirus that has caused unprecedented epidemics worldwide. Here, we took interdisciplinary approaches to elucidate the CHIKV determinants that subvert mac...

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Detalles Bibliográficos
Autores principales: Yao, Zhenlan, Ramachandran, Sangeetha, Huang, Serina, Jami-Alahmadi, Yasaman, Wohlschlegel, James A., Li, Melody M.H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312455/
https://www.ncbi.nlm.nih.gov/pubmed/37398144
http://dx.doi.org/10.1101/2023.05.29.542714