Small Molecule in situ Resin Capture – A Compound First Approach to Natural Product Discovery

Microbial natural products remain an important resource for drug discovery. Yet, commonly employed discovery techniques are plagued by the rediscovery of known compounds, the relatively few microbes that can be cultured, and laboratory growth conditions that do not elicit biosynthetic gene expressio...

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Detalles Bibliográficos
Autores principales: Bogdanov, Alexander, Salib, Mariam N., Chase, Alexander B., Hammerlindl, Heinz, Muskat, Mitchell N., Luedtke, Stephanie, Barbosa da Silva, Elany, O’Donoghue, Anthony J., Wu, Lani F., Altschuler, Steven J., Molinski, Tadeusz F., Jensen, Paul R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312467/
https://www.ncbi.nlm.nih.gov/pubmed/37398257
http://dx.doi.org/10.1101/2023.03.02.530684

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312467/
https://www.ncbi.nlm.nih.gov/pubmed/37398257
http://dx.doi.org/10.1101/2023.03.02.530684

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