Invasion of spontaneous germinal centers by naive B cells is rapid and persistent

In autoreactive germinal centers (GC) initiated by a single rogue B cell clone, wild-type B cells expand and give rise to clones that target other autoantigens, known as epitope spreading. The chronic, progressive nature of epitope spreading calls for early interventions, but the kinetics and molecu...

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Detalles Bibliográficos
Autores principales: van den Broek, T., Oleinika, K., Rahmayanti, S., Castrillon, C., van der Poel, C.E., Carroll, M.C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312503/
https://www.ncbi.nlm.nih.gov/pubmed/37398148
http://dx.doi.org/10.1101/2023.05.30.542805

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312503/
https://www.ncbi.nlm.nih.gov/pubmed/37398148
http://dx.doi.org/10.1101/2023.05.30.542805

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