Fetally-encoded GDF15 and maternal GDF15 sensitivity are major determinants of nausea and vomiting in human pregnancy

Human pregnancy is frequently accompanied by nausea and vomiting that may become severe and life-threatening, as in hyperemesis gravidarum (HG), the cause of which is unknown. Growth Differentiation Factor-15 (GDF15), a hormone known to act on the hindbrain to cause emesis, is highly expressed in th...

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Detalles Bibliográficos
Autores principales: Fejzo, M, Rocha, N, Cimino, I, Lockhart, SM, Petry, C, Kay, RG, Burling, K, Barker, P, George, AL, Yasara, N, Premawardhena, A, Gong, S, Cook, E, Rainbow, K, Withers, DJ, Cortessis, V, Mullin, PM, MacGibbon, KW, Jin, E, Kam, A, Campbell, A, Polasek, O, Tzoneva, G, Gribble, FM, Yeo, GSH, Lam, BYH, Saudek, V, Hughes, IA, Ong, KK, Perry, JRB, Sutton Cole, A, Baumgarten, M, Welsh, P, Sattar, N, Smith, GCS, Charnock Jones, DS, Coll, AP, Meek, CL, Mettananda, S, Hayward, C, Mancuso, N, O’Rahilly, S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312505/
https://www.ncbi.nlm.nih.gov/pubmed/37398065
http://dx.doi.org/10.1101/2023.06.02.542661

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312505/
https://www.ncbi.nlm.nih.gov/pubmed/37398065
http://dx.doi.org/10.1101/2023.06.02.542661

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