Wolbachia-induced inhibition of O’nyong nyong virus in Anopheles mosquitoes is mediated by Toll signaling and modulated by cholesterol

Enhanced host immunity and competition for metabolic resources are two main competing hypotheses for the mechanism of Wolbachia-mediated pathogen inhibition in arthropods. Using an Anopheles mosquito - somatic Wolbachia infection - O’nyong nyong virus (ONNV) model, we demonstrate that the mechanism...

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Detalles Bibliográficos
Autores principales: Pujhari, Sujit, Hughes, Grant L, Pakpour, Nazzy, Suzuki, Yasutsugu, Rasgon, Jason L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312510/
https://www.ncbi.nlm.nih.gov/pubmed/37397989
http://dx.doi.org/10.1101/2023.05.31.543096

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312510/
https://www.ncbi.nlm.nih.gov/pubmed/37397989
http://dx.doi.org/10.1101/2023.05.31.543096

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