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Wolbachia-induced inhibition of O’nyong nyong virus in Anopheles mosquitoes is mediated by Toll signaling and modulated by cholesterol
Enhanced host immunity and competition for metabolic resources are two main competing hypotheses for the mechanism of Wolbachia-mediated pathogen inhibition in arthropods. Using an Anopheles mosquito - somatic Wolbachia infection - O’nyong nyong virus (ONNV) model, we demonstrate that the mechanism...
Autores principales: | Pujhari, Sujit, Hughes, Grant L, Pakpour, Nazzy, Suzuki, Yasutsugu, Rasgon, Jason L |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312510/ https://www.ncbi.nlm.nih.gov/pubmed/37397989 http://dx.doi.org/10.1101/2023.05.31.543096 |
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