In vivo evolution of a Klebsiella pneumoniae capsule defect promotes complement-mediated opsono-phagocytosis and persistence during recurrent infection

Klebsiella pneumoniae carbapenemase-producing K. pneumoniae (KPC-Kp) bloodstream infections rarely overwhelm the host but are associated with high mortality. The complement system is a key host defense against bloodstream infection. However, there are varying reports of serum resistance among KPC-Kp...

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Detalles Bibliográficos
Autores principales: Bain, William, Ahn, Brian, Peñaloza, Hernán F., McElheny, Christi L., Tolman, Nathanial, van der Geest, Rick, Gonzalez-Ferrer, Shekina, Chen, Nathalie, An, Xiaojing, Hosuru, Ria, Tabary, Mohammadreza, Papke, Erin, Kohli, Naina, Farooq, Nauman, Bachman, William, Olonisakin, Tolani F., Xiong, Zeyu, Griffith, Marissa P., Sullivan, Mara, Franks, Jonathan, Mustapha, Mustapha M., Iovleva, Alina, Suber, Tomeka, Shanks, Robert Q., Ferreira, Viviana P., Stolz, Donna B., Van Tyne, Daria, Doi, Yohei, Lee, Janet S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312532/
https://www.ncbi.nlm.nih.gov/pubmed/37398264
http://dx.doi.org/10.1101/2023.05.31.542722

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312532/
https://www.ncbi.nlm.nih.gov/pubmed/37398264
http://dx.doi.org/10.1101/2023.05.31.542722

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