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A framework for identifying fertility gene targets for mammalian pest control

1. Fertility-targeted gene drives have been proposed as an ethical genetic approach for managing wild populations of vertebrate pests for public health and conservation benefit. 2. This manuscript introduces a framework to identify and evaluate target gene suitability based on biological gene functi...

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Detalles Bibliográficos
Autores principales: Clark, Anna C, Alexander, Alana, Edison, Rey, Esvelt, Kevin, Kamau, Sebastian, Dutoit, Ludovic, Champer, Jackson, Champer, Samuel E, Messer, Philipp W, Gemmell, Neil J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312551/
https://www.ncbi.nlm.nih.gov/pubmed/37398071
http://dx.doi.org/10.1101/2023.05.30.542751