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KDM3A and KDM3B Maintain Naïve Pluripotency Through the Regulation of Alternative Splicing

Histone modifying enzymes play a central role in maintaining cell identity by establishing a conducive chromatin environment for lineage specific transcription factor activity. Pluripotent embryonic stem cells (ESCs) identity is characterized by lower abundance of gene repression associated histone...

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Detalles Bibliográficos
Autores principales: Dillingham, Caleb, Cormaty, Harshini, Morgan, Ellen, Esgdaille, Dakarai, Boutz, Paul, Sridharan, Rupa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312572/
https://www.ncbi.nlm.nih.gov/pubmed/37398291
http://dx.doi.org/10.1101/2023.05.31.543088