Cargando…

A single polymorphic residue in humans underlies species-specific restriction of HSV-1 by the antiviral protein MxB

Myxovirus resistance proteins (MxA and MxB) are interferon-induced proteins that exert antiviral activity against a diverse range of RNA and DNA viruses. In primates, MxA has been shown to inhibit myxoviruses, bunyaviruses, and hepatitis B virus, whereas MxB restricts retroviruses and herpesviruses....

Descripción completa

Detalles Bibliográficos
Autores principales: Bayer, Avraham, Child, Stephanie J., Malik, Harmit S., Geballe, Adam P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312577/
https://www.ncbi.nlm.nih.gov/pubmed/37398298
http://dx.doi.org/10.1101/2023.05.30.542951