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A single polymorphic residue in humans underlies species-specific restriction of HSV-1 by the antiviral protein MxB
Myxovirus resistance proteins (MxA and MxB) are interferon-induced proteins that exert antiviral activity against a diverse range of RNA and DNA viruses. In primates, MxA has been shown to inhibit myxoviruses, bunyaviruses, and hepatitis B virus, whereas MxB restricts retroviruses and herpesviruses....
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312577/ https://www.ncbi.nlm.nih.gov/pubmed/37398298 http://dx.doi.org/10.1101/2023.05.30.542951 |