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De novo design of modular protein hydrogels with programmable intra- and extracellular viscoelasticity
Relating the macroscopic properties of protein-based materials to their underlying component microstructure is an outstanding challenge. Here, we exploit computational design to specify the size, flexibility, and valency of de novo protein building blocks, as well as the interaction dynamics between...
Autores principales: | Mout, Rubul, Bretherton, Ross C., Decarreau, Justin, Lee, Sangmin, Edman, Natasha I., Ahlrichs, Maggie, Hsia, Yang, Sahtoe, Danny D., Ueda, George, Gregorio, Nicole, Sharma, Alee, Schulman, Rebecca, DeForest, Cole A., Baker, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312586/ https://www.ncbi.nlm.nih.gov/pubmed/37398067 http://dx.doi.org/10.1101/2023.06.02.543449 |
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