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Cryo-EM structures of Kv1.2 potassium channels, conducting and non-conducting
We present near-atomic-resolution cryo-EM structures of the mammalian voltage-gated potassium channel Kv1.2 in open, C-type inactivated, toxin-blocked and sodium-bound states at 3.2 Å, 2.5 Å, 2.8 Å, and 2.9Å. These structures, all obtained at nominally zero membrane potential in detergent micelles,...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312591/ https://www.ncbi.nlm.nih.gov/pubmed/37398110 http://dx.doi.org/10.1101/2023.06.02.543446 |